We conducted a prospective, observational clinical validation study to assess the diagnostic accuracy of the AI algorithm (ADAE) in predicting melanoma from dermoscopy skin lesion images. Patients who had consented for a skin biopsy to exclude melanoma were eligible. All lesions underwent biopsy.
{ "acquisition_day": 1, "age_approx": 75, "anatom_site_general": "lower extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "2.80", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_9609940", "melanocytic": true, "patient_id": "IP_2711304", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 55, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "4.40", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_3308221", "melanocytic": true, "patient_id": "IP_8182508", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 55, "anatom_site_general": "anterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "5.00", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_4232045", "melanocytic": true, "patient_id": "IP_8182508", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 55, "anatom_site_general": "upper extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "4.70", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_2536774", "melanocytic": true, "patient_id": "IP_8182508", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 40, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "7.60", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_2833600", "melanocytic": true, "patient_id": "IP_1268919", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 70, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "9.30", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_0733293", "melanocytic": true, "patient_id": "IP_3633451", "personal_hx_mm": true, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 55, "anatom_site_general": "anterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "6.00", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_0862141", "melanocytic": true, "patient_id": "IP_0251730", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 60, "anatom_site_general": "upper extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "3.50", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_0814520", "melanocytic": true, "patient_id": "IP_6213063", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 55, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "3.70", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "seborrheic keratosis", "diagnosis_1": "Benign", "diagnosis_2": "Collision - Only benign proliferations", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_1715841", "melanocytic": true, "patient_id": "IP_6306618", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 60, "anatom_site_general": "lower extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "4.60", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_7003382", "melanocytic": true, "patient_id": "IP_3124248", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 50, "anatom_site_general": "upper extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "4.10", "concomitant_biopsy": true, "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "IV", "image_type": "dermoscopic", "lesion_id": "IL_6128796", "melanocytic": true, "patient_id": "IP_0456231", "personal_hx_mm": false, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 30, "anatom_site_general": "anterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "6.20", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_2664791", "melanocytic": true, "patient_id": "IP_5117877", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 65, "anatom_site_general": "lower extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "4.80", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "lentigo NOS", "diagnosis_1": "Benign", "diagnosis_2": "Flat melanotic pigmentations - not melanocytic nevus", "diagnosis_3": "Lentigo NOS", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_5779701", "melanocytic": true, "patient_id": "IP_0341102", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 65, "anatom_site_general": "anterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "19.70", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "seborrheic keratosis", "diagnosis_1": "Benign", "diagnosis_2": "Collision - Only benign proliferations", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_5923307", "melanocytic": true, "patient_id": "IP_0341102", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 65, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "5.80", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Collision - Only benign proliferations", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_9799837", "melanocytic": true, "patient_id": "IP_3003160", "personal_hx_mm": false, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 65, "anatom_site_general": "lateral torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "4.20", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_5374153", "melanocytic": true, "patient_id": "IP_3003160", "personal_hx_mm": false, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 45, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "12.50", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "atypical melanocytic proliferation", "diagnosis_1": "Indeterminate", "diagnosis_2": "Indeterminate melanocytic proliferations", "diagnosis_3": "Atypical melanocytic neoplasm", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "I", "image_type": "dermoscopic", "lesion_id": "IL_6910976", "melanocytic": true, "patient_id": "IP_4889048", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 40, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "14.60", "concomitant_biopsy": true, "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_5981967", "melanocytic": true, "patient_id": "IP_1590637", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 60, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "3.90", "concomitant_biopsy": true, "dermoscopic_type": "non-contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_3720070", "melanocytic": true, "patient_id": "IP_3670868", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 50, "anatom_site_general": "upper extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "4.80", "concomitant_biopsy": true, "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_6455061", "melanocytic": true, "patient_id": "IP_4330259", "personal_hx_mm": false, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 65, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "2.60", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_4130348", "melanocytic": true, "patient_id": "IP_8607082", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 65, "anatom_site_general": "anterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "9.80", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_2566173", "melanocytic": true, "patient_id": "IP_8607082", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 30, "anatom_site_general": "lower extremity", "benign_malignant": "malignant", "clin_size_long_diam_mm": "4.50", "concomitant_biopsy": true, "dermoscopic_type": "non-contact polarized", "diagnosis": "melanoma", "diagnosis_1": "Malignant", "diagnosis_2": "Malignant melanocytic proliferations (Melanoma)", "diagnosis_3": "Melanoma Invasive", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_4781357", "mel_class": "invasive melanoma", "mel_thick_mm": "0.20", "mel_ulcer": false, "melanocytic": true, "patient_id": "IP_2560383", "personal_hx_mm": false, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 40, "anatom_site_general": "anterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "3.90", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_9451871", "melanocytic": true, "patient_id": "IP_0814408", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 40, "anatom_site_general": "upper extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "6.70", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Combined", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_8854666", "melanocytic": true, "nevus_type": "combined", "patient_id": "IP_0814408", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 40, "anatom_site_general": "lower extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "5.20", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_1318025", "melanocytic": true, "patient_id": "IP_0814408", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 40, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "5.90", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_7193005", "melanocytic": true, "patient_id": "IP_0814408", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 70, "anatom_site_general": "upper extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "6.00", "concomitant_biopsy": true, "diagnosis": "dermatofibroma", "diagnosis_1": "Benign", "diagnosis_2": "Benign soft tissue proliferations - Fibro-histiocytic", "diagnosis_3": "Dermatofibroma", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "I", "image_type": "dermoscopic", "lesion_id": "IL_7865798", "melanocytic": false, "patient_id": "IP_2768316", "personal_hx_mm": true, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 70, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "15.50", "concomitant_biopsy": true, "dermoscopic_type": "non-contact polarized", "diagnosis": "seborrheic keratosis", "diagnosis_1": "Benign", "diagnosis_2": "Collision - Only benign proliferations", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "I", "image_type": "dermoscopic", "lesion_id": "IL_7694612", "melanocytic": true, "patient_id": "IP_2768316", "personal_hx_mm": true, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 85, "anatom_site_general": "head/neck", "benign_malignant": "malignant", "clin_size_long_diam_mm": "13.20", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "melanoma", "diagnosis_1": "Malignant", "diagnosis_2": "Malignant melanocytic proliferations (Melanoma)", "diagnosis_3": "Melanoma in situ", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_4362949", "mel_class": "melanoma in situ", "melanocytic": true, "patient_id": "IP_5621209", "personal_hx_mm": true, "sex": "male" }