We conducted a prospective, observational clinical validation study to assess the diagnostic accuracy of the AI algorithm (ADAE) in predicting melanoma from dermoscopy skin lesion images. Patients who had consented for a skin biopsy to exclude melanoma were eligible. All lesions underwent biopsy.
{ "acquisition_day": 1, "age_approx": 75, "anatom_site_general": "head/neck", "benign_malignant": "benign", "clin_size_long_diam_mm": "2.90", "concomitant_biopsy": true, "diagnosis": "lentigo NOS", "diagnosis_1": "Benign", "diagnosis_2": "Flat melanotic pigmentations - not melanocytic nevus", "diagnosis_3": "Lentigo NOS", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_4622988", "melanocytic": true, "patient_id": "IP_4601401", "personal_hx_mm": false, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 50, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "9.70", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_4859494", "melanocytic": true, "patient_id": "IP_9744773", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 65, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "4.40", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_8457446", "melanocytic": true, "patient_id": "IP_8804321", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 60, "anatom_site_general": "upper extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "6.00", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "lentigo NOS", "diagnosis_1": "Benign", "diagnosis_2": "Flat melanotic pigmentations - not melanocytic nevus", "diagnosis_3": "Lentigo NOS", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_1288393", "melanocytic": true, "patient_id": "IP_8554596", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 50, "anatom_site_general": "lower extremity", "benign_malignant": "malignant", "clin_size_long_diam_mm": "3.80", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "basal cell carcinoma", "diagnosis_1": "Malignant", "diagnosis_2": "Malignant adnexal epithelial proliferations - Follicular", "diagnosis_3": "Basal cell carcinoma", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_8951295", "melanocytic": false, "patient_id": "IP_0748604", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 50, "anatom_site_general": "head/neck", "benign_malignant": "benign", "clin_size_long_diam_mm": "10.30", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "lentigo NOS", "diagnosis_1": "Benign", "diagnosis_2": "Flat melanotic pigmentations - not melanocytic nevus", "diagnosis_3": "Lentigo NOS", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_7053045", "melanocytic": true, "patient_id": "IP_0748604", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 70, "anatom_site_general": "head/neck", "benign_malignant": "benign", "clin_size_long_diam_mm": "4.20", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "lentigo NOS", "diagnosis_1": "Benign", "diagnosis_2": "Flat melanotic pigmentations - not melanocytic nevus", "diagnosis_3": "Lentigo NOS", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_0386573", "melanocytic": true, "patient_id": "IP_5783656", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 65, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "4.00", "concomitant_biopsy": true, "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_5469719", "melanocytic": true, "patient_id": "IP_6848590", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 20, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "6.00", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_3226437", "melanocytic": true, "patient_id": "IP_0484521", "personal_hx_mm": false, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 85, "anatom_site_general": "head/neck", "benign_malignant": "benign", "clin_size_long_diam_mm": "17.90", "concomitant_biopsy": true, "diagnosis": "lentigo NOS", "diagnosis_1": "Benign", "diagnosis_2": "Flat melanotic pigmentations - not melanocytic nevus", "diagnosis_3": "Lentigo NOS", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_7009449", "melanocytic": true, "patient_id": "IP_7498505", "personal_hx_mm": false, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 85, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "4.00", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_5424222", "melanocytic": true, "patient_id": "IP_7498505", "personal_hx_mm": false, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 70, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "5.30", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "dermatofibroma", "diagnosis_1": "Benign", "diagnosis_2": "Benign soft tissue proliferations - Fibro-histiocytic", "diagnosis_3": "Dermatofibroma", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_7944142", "melanocytic": false, "patient_id": "IP_4316317", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 70, "anatom_site_general": "lower extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "4.40", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "dermatofibroma", "diagnosis_1": "Benign", "diagnosis_2": "Benign soft tissue proliferations - Fibro-histiocytic", "diagnosis_3": "Dermatofibroma", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_1028415", "melanocytic": false, "patient_id": "IP_4316317", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 55, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "7.30", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_4943802", "melanocytic": true, "patient_id": "IP_2573038", "personal_hx_mm": false, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 50, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "5.30", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_6436659", "melanocytic": true, "patient_id": "IP_9611346", "personal_hx_mm": false, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 60, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "4.90", "concomitant_biopsy": true, "dermoscopic_type": "non-contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "IV", "image_type": "dermoscopic", "lesion_id": "IL_8748908", "melanocytic": true, "patient_id": "IP_1472711", "personal_hx_mm": false, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 65, "anatom_site_general": "posterior torso", "benign_malignant": "malignant", "clin_size_long_diam_mm": "8.00", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "melanoma", "diagnosis_1": "Malignant", "diagnosis_2": "Malignant melanocytic proliferations (Melanoma)", "diagnosis_3": "Melanoma Invasive", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "I", "image_type": "dermoscopic", "lesion_id": "IL_3529855", "mel_class": "invasive melanoma", "mel_thick_mm": "0.20", "melanocytic": true, "patient_id": "IP_6924850", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1100, "age_approx": 65, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "3.50", "concomitant_biopsy": true, "dermoscopic_type": "contact non-polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_2171415", "melanocytic": true, "patient_id": "IP_1645936", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 65, "anatom_site_general": "upper extremity", "benign_malignant": "malignant", "clin_size_long_diam_mm": "15.10", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "melanoma", "diagnosis_1": "Malignant", "diagnosis_2": "Malignant melanocytic proliferations (Melanoma)", "diagnosis_3": "Melanoma Invasive", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "I", "image_type": "dermoscopic", "lesion_id": "IL_2413085", "mel_class": "invasive melanoma", "mel_thick_mm": "0.30", "melanocytic": true, "patient_id": "IP_6924850", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 65, "anatom_site_general": "posterior torso", "benign_malignant": "malignant", "clin_size_long_diam_mm": "9.60", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "melanoma", "diagnosis_1": "Malignant", "diagnosis_2": "Malignant melanocytic proliferations (Melanoma)", "diagnosis_3": "Melanoma Invasive", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "I", "image_type": "dermoscopic", "lesion_id": "IL_1276989", "mel_class": "invasive melanoma", "mel_thick_mm": "0.30", "mel_ulcer": false, "melanocytic": true, "patient_id": "IP_6924850", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 40, "anatom_site_general": "upper extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "5.70", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_8564680", "melanocytic": true, "patient_id": "IP_0260261", "personal_hx_mm": false, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 65, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "6.10", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "lentigo NOS", "diagnosis_1": "Benign", "diagnosis_2": "Flat melanotic pigmentations - not melanocytic nevus", "diagnosis_3": "Lentigo NOS", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_0927947", "melanocytic": true, "patient_id": "IP_4732506", "personal_hx_mm": true, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 65, "anatom_site_general": "lower extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "10.60", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_1232146", "melanocytic": true, "patient_id": "IP_9274667", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 65, "anatom_site_general": "lateral torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "7.30", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "seborrheic keratosis", "diagnosis_1": "Benign", "diagnosis_2": "Benign epidermal proliferations", "diagnosis_3": "Seborrheic keratosis", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_9004463", "melanocytic": false, "patient_id": "IP_9274667", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 65, "anatom_site_general": "posterior torso", "benign_malignant": "indeterminate/benign", "clin_size_long_diam_mm": "7.70", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "atypical melanocytic proliferation", "diagnosis_1": "Indeterminate", "diagnosis_2": "Indeterminate melanocytic proliferations", "diagnosis_3": "Atypical melanocytic neoplasm", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_2602296", "melanocytic": true, "patient_id": "IP_9274667", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 65, "anatom_site_general": "posterior torso", "benign_malignant": "indeterminate/benign", "clin_size_long_diam_mm": "8.40", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "atypical melanocytic proliferation", "diagnosis_1": "Indeterminate", "diagnosis_2": "Indeterminate melanocytic proliferations", "diagnosis_3": "Atypical melanocytic neoplasm", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_4045479", "melanocytic": true, "patient_id": "IP_9274667", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 70, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "3.50", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_2829983", "melanocytic": true, "patient_id": "IP_0801144", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 25, "anatom_site_general": "lower extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "5.40", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_1955791", "melanocytic": true, "patient_id": "IP_3158554", "personal_hx_mm": false, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 25, "anatom_site_general": "upper extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "4.50", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_5479142", "melanocytic": true, "patient_id": "IP_3158554", "personal_hx_mm": false, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 25, "anatom_site_general": "upper extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "2.80", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_7158723", "melanocytic": true, "patient_id": "IP_3158554", "personal_hx_mm": false, "sex": "male" }