We conducted a prospective, observational clinical validation study to assess the diagnostic accuracy of the AI algorithm (ADAE) in predicting melanoma from dermoscopy skin lesion images. Patients who had consented for a skin biopsy to exclude melanoma were eligible. All lesions underwent biopsy.
{ "acquisition_day": 1, "age_approx": 75, "anatom_site_general": "head/neck", "benign_malignant": "benign", "clin_size_long_diam_mm": "2.70", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "lentigo NOS", "diagnosis_1": "Benign", "diagnosis_2": "Flat melanotic pigmentations - not melanocytic nevus", "diagnosis_3": "Lentigo NOS", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_2102236", "melanocytic": true, "patient_id": "IP_3792900", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 65, "anatom_site_general": "upper extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "6.40", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "lentigo NOS", "diagnosis_1": "Benign", "diagnosis_2": "Flat melanotic pigmentations - not melanocytic nevus", "diagnosis_3": "Lentigo NOS", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_6596914", "melanocytic": true, "patient_id": "IP_3954818", "personal_hx_mm": true, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 55, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "4.00", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_1203183", "melanocytic": true, "patient_id": "IP_2804258", "personal_hx_mm": false, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 80, "anatom_site_general": "lower extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "6.00", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "dermatofibroma", "diagnosis_1": "Benign", "diagnosis_2": "Benign soft tissue proliferations - Fibro-histiocytic", "diagnosis_3": "Dermatofibroma", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "I", "image_type": "dermoscopic", "lesion_id": "IL_9773243", "melanocytic": false, "patient_id": "IP_2869031", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 55, "anatom_site_general": "head/neck", "benign_malignant": "benign", "clin_size_long_diam_mm": "10.10", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "actinic keratosis", "diagnosis_1": "Indeterminate", "diagnosis_2": "Indeterminate epidermal proliferations", "diagnosis_3": "Solar or actinic keratosis", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_9782109", "melanocytic": true, "patient_id": "IP_3372776", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 75, "anatom_site_general": "posterior torso", "benign_malignant": "malignant", "clin_size_long_diam_mm": "9.20", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "melanoma", "diagnosis_1": "Malignant", "diagnosis_2": "Malignant melanocytic proliferations (Melanoma)", "diagnosis_3": "Melanoma in situ", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_8770408", "mel_class": "melanoma in situ", "melanocytic": true, "patient_id": "IP_9653634", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 80, "anatom_site_general": "head/neck", "benign_malignant": "benign", "clin_size_long_diam_mm": "10.70", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "lentigo NOS", "diagnosis_1": "Benign", "diagnosis_2": "Flat melanotic pigmentations - not melanocytic nevus", "diagnosis_3": "Lentigo NOS", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_9878424", "melanocytic": true, "patient_id": "IP_2127737", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 75, "anatom_site_general": "lower extremity", "benign_malignant": "malignant", "clin_size_long_diam_mm": "4.30", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "melanoma", "diagnosis_1": "Malignant", "diagnosis_2": "Malignant melanocytic proliferations (Melanoma)", "diagnosis_3": "Melanoma Invasive", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_0810303", "mel_class": "invasive melanoma", "mel_thick_mm": "0.25", "melanocytic": true, "patient_id": "IP_5316403", "personal_hx_mm": true, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 80, "anatom_site_general": "head/neck", "benign_malignant": "indeterminate/malignant", "clin_size_long_diam_mm": "11.20", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "melanoma", "diagnosis_1": "Malignant", "diagnosis_2": "Malignant melanocytic proliferations (Melanoma)", "diagnosis_3": "Melanoma in situ", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_2442391", "mel_class": "melanoma in situ", "melanocytic": true, "patient_id": "IP_0115444", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 80, "anatom_site_general": "posterior torso", "benign_malignant": "malignant", "clin_size_long_diam_mm": "14.60", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "melanoma", "diagnosis_1": "Malignant", "diagnosis_2": "Malignant melanocytic proliferations (Melanoma)", "diagnosis_3": "Melanoma Invasive", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "I", "image_type": "dermoscopic", "lesion_id": "IL_1428795", "mel_class": "invasive melanoma", "mel_thick_mm": "0.40", "mel_ulcer": false, "melanocytic": true, "patient_id": "IP_8685501", "personal_hx_mm": true, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 30, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "5.60", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_5446220", "melanocytic": true, "patient_id": "IP_8333628", "personal_hx_mm": false, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 70, "anatom_site_general": "upper extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "4.10", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_0795030", "melanocytic": true, "patient_id": "IP_1472169", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 60, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "6.70", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "IV", "image_type": "dermoscopic", "lesion_id": "IL_7880698", "melanocytic": true, "patient_id": "IP_8105755", "personal_hx_mm": false, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 60, "anatom_site_general": "anterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "7.70", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "IV", "image_type": "dermoscopic", "lesion_id": "IL_1813390", "melanocytic": true, "patient_id": "IP_8105755", "personal_hx_mm": false, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 65, "anatom_site_general": "anterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "7.50", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_5870035", "melanocytic": true, "patient_id": "IP_4593426", "personal_hx_mm": true, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 55, "anatom_site_general": "posterior torso", "benign_malignant": "indeterminate/malignant", "clin_size_long_diam_mm": "9.80", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "melanoma", "diagnosis_1": "Malignant", "diagnosis_2": "Malignant melanocytic proliferations (Melanoma)", "diagnosis_3": "Melanoma in situ", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_1566495", "mel_class": "melanoma in situ", "melanocytic": true, "patient_id": "IP_0733130", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 55, "anatom_site_general": "anterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "3.00", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_5000455", "melanocytic": true, "patient_id": "IP_0733130", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 60, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "9.50", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "IV", "image_type": "dermoscopic", "lesion_id": "IL_5928320", "melanocytic": true, "patient_id": "IP_1566965", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 60, "anatom_site_general": "lower extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "2.80", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_6951090", "melanocytic": true, "patient_id": "IP_6094585", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 60, "anatom_site_general": "anterior torso", "benign_malignant": "indeterminate/benign", "clin_size_long_diam_mm": "4.10", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_4608739", "melanocytic": true, "patient_id": "IP_6094585", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 70, "anatom_site_general": "lower extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "5.40", "concomitant_biopsy": true, "dermoscopic_type": "non-contact polarized", "diagnosis": "lentigo NOS", "diagnosis_1": "Benign", "diagnosis_2": "Flat melanotic pigmentations - not melanocytic nevus", "diagnosis_3": "Lentigo NOS", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_0894093", "melanocytic": true, "patient_id": "IP_0540302", "personal_hx_mm": true, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 80, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "7.20", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_6030405", "melanocytic": true, "patient_id": "IP_8819261", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 80, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "8.20", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_2802861", "melanocytic": true, "patient_id": "IP_8819261", "personal_hx_mm": true, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 70, "anatom_site_general": "lower extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "11.30", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_3314187", "melanocytic": true, "patient_id": "IP_7410598", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 55, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "1.80", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "seborrheic keratosis", "diagnosis_1": "Benign", "diagnosis_2": "Benign epidermal proliferations", "diagnosis_3": "Seborrheic keratosis", "diagnosis_confirm_type": "histopathology", "family_hx_mm": false, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_0231258", "melanocytic": false, "patient_id": "IP_2465945", "personal_hx_mm": false, "sex": "male" }
{ "acquisition_day": 1, "age_approx": 30, "anatom_site_general": "posterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "5.20", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_8728500", "melanocytic": true, "patient_id": "IP_7666532", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 30, "anatom_site_general": "anterior torso", "benign_malignant": "benign", "clin_size_long_diam_mm": "4.00", "concomitant_biopsy": true, "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_4": "Nevus, Atypical, Dysplastic, or Clark", "diagnosis_5": "Nevus, Atypical", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_5664784", "melanocytic": true, "patient_id": "IP_7666532", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 30, "anatom_site_general": "lower extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "2.10", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "III", "image_type": "dermoscopic", "lesion_id": "IL_5099201", "melanocytic": true, "patient_id": "IP_7666532", "personal_hx_mm": false, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 85, "anatom_site_general": "lower extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "2.90", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "nevus", "diagnosis_1": "Benign", "diagnosis_2": "Benign melanocytic proliferations", "diagnosis_3": "Nevus", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_4046290", "melanocytic": true, "patient_id": "IP_9653442", "personal_hx_mm": true, "sex": "female" }
{ "acquisition_day": 1, "age_approx": 85, "anatom_site_general": "lower extremity", "benign_malignant": "benign", "clin_size_long_diam_mm": "4.40", "concomitant_biopsy": true, "dermoscopic_type": "contact polarized", "diagnosis": "lentigo NOS", "diagnosis_1": "Benign", "diagnosis_2": "Flat melanotic pigmentations - not melanocytic nevus", "diagnosis_3": "Lentigo NOS", "diagnosis_confirm_type": "histopathology", "family_hx_mm": true, "fitzpatrick_skin_type": "II", "image_type": "dermoscopic", "lesion_id": "IL_0492947", "melanocytic": true, "patient_id": "IP_9653442", "personal_hx_mm": true, "sex": "female" }